FRA Butyrin Hybrid combines the benefits of glycerides of butyric acid on intestinal integrity and pathogen control in one unique concept.
The use of antibiotics is restricted due to the increasing number of resistant bacteria and therefore other solutions must be found. A dietary feed supplement that supports intestinal health by stimulating intestinal development and reducing the growth of pathogenic bacteria, thereby improving animal performance and production is of high interest.
Tributyrin ensures that high amounts of butyric acid are delivered in the small intestine, where it will strengthen the gut barrier and stimulate gut development.
Monobutyrin is know for its antibacterial effect towards Gram-negative bacteria, improving animal resilience against pathogenic challenges.
Tributyrin induces the formation of tight junctions, which improves the intestinal barrier function. This allows nutrients to be absorbed, while keeping toxins and pathogens in the lumen. Furthermore, tributyrin improves villi development, increasing the surface area for nutrient absorption.
Monobutyrin has an anti-bacterial effect against most Gram-negative bacteria. It has been shown for instance that glycerides of C4 were able to reduce the adhesion of C. jejuni and S. Typhimurium to chicken enterocytes in vitro.
FRA Butyrin Hybrid combines the beneficial effects of tributyrin and monobutyrin. Tributyrin enhances gut development and integrity by delivering butyrate in the small intestine. Butyric acid serves as energy source for the epithelium cells and stimulates villi growth and recovery. It also strengthens the gut barrier function, limiting the risk of translocation of pathogens. In addition, monobutyrin will stimulate animal resilience against pathogenic challenges by Gram-negative bacteria via its antibacterial effect.
Sustainable and efficient animal production is important in poultry husbandry. However, in commercial flocks, animals are subjected to multiple stress factors such as high stocking densities and suboptimal climate conditions which makes them highly susceptible for pathogens. This results in decreased growth performance, high mortality rates and a lower profitability. The use of antibiotics is restricted due to the increasing number of resistant bacteria and therefore other solutions must be found. A dietary feed supplement which supports intestinal health by stimulating intestinal development and reducing the growth of pathogenic bacteria, thereby improving poultry performance and production is of high interest.
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