Selisseo®: The gold standard in Organic Selenium

Selisseo® is a unique, pure and reliable organic form of selenium that helps animals fight oxidative stress.

  • Increases the selenium status
  • Improves the antioxidant protection
Click on the species to explore the benefits:
✅ Link copied to clipboard!
Looking for more information?

Product names and availability may vary by region, please contact your local Adisseo representative for more information.

Unlock the power of oxidative stress resistance with Selisseo®

Selisseo® contains 100% hydroxy-selenomethionine (OH-SeMet), a pure and highly available form of organic selenium that helps animals combat oxidative stress. Selenium (Se) is an essential nutrient for life and it has been established that 0.1-0.3 ppm is necessary to support basic functions. While inorganic Se sources such as sodium selenite are commonly used as feed supplements, recent research has confirmed that organic Se sources, and in particular selenomethionine (SeMet) and OH-SeMet are absorbed more efficiently.

 


 

  • On average, Selenium Yeast products contain 60% SeMet and the amount of SeMet varies from batch to batch, while Selisseo® consistently provides 100% OH-SeMet.

Key benefits

Stress management

Stress management

What really makes Selisseo® stand out is its ability to help animals cope better with stress by storing more SeMet in their tissues. This key feature boosts stress resistance to maintain the growth performance under challenging conditions.

Qualitative end products

Qualitative end products

Elevate end-product quality with Selisseo®. Your assurance of premium quality meat, eggs and milk.

Reproductive performance

Reproductive performance

Selisseo® enhances reproductive performance, towards healthier offspring and sustained breeding success.

A reliable source of organic selenium for optimal nutrition and performance

The purpose of organic Selenium (Se) is to provide Se in the form of selenomethionine (SeMet) as this is the only form of Se that can both be utilized for selenoprotein production and safely stored in the animal body to build up Se reserves. Animals can utilize its Se reserves during times of increased oxidative stress, when the need for Se is higher. These Se reserves are key to maximizing all the benefits of Se.

However, only 63% of the Seleno-Yeast of Se is in the form of SeMet and this percentage can be quite variable.​

On the other hand, Selisseo® provides 100% of Se as OH-SeMet, thus ensuring an optimal Se reserve and supporting the performance of animals.

image1

Key figures

100%

Selisseo® provides 100% of Selenium as OH-SeMet

60+

Backed-up by science: 60+ peer-reviewed scientific papers

Introduction

Help animals combat oxidative stress

Selisseo® is the only hydroxy-selenomethionine on the market, fully delivering the benefits of organic selenium for enhanced stress resistance and immunity, optimal growth, better reproduction performance and higher quality of end-products.

Helpful resources

Top line
Adisseo Claims New Study Finds Inorganic Selenium Content in SeYeast Higher Than Previously Believed

Adisseo Claims New Study Finds Inorganic Selenium Content in SeYeast Higher Than Previously Believed

Tag Separator
Technical article

Know more about Selisseo® action on your species

Selisseo® benefits for poultry per subspecie

Breeders

Selisseo® improves the reproduction performance of breeders:

🞄 Fertility rate vs SS and SY
🞄 Hatchability vs SS and SY
🞄 Antioxidant status vs SS thus leading to a greater robustness of day-old chicks

Broilers

Selisseo® alleviates the effects of stress on broiler growth:

🞄 Final body weight: Consistently improved compared to SS and SY
🞄 FCR: Consistently improved compared to SS and SY
🞄 Se deposition in the muscles vs SS and SY

Layers

Selisseo® sustains a better egg production in aging layers:

🞄 Egg production: More eggs/hen vs SS and SY
🞄 FCR vs SS and SY
🞄 Se-enriched egg: higher Se concentration in the egg vs SS and SY

Helpful resources

Top line
Viral threats in poultry

Viral threats in poultry

Tag Separator
Technical article
Top line
Improvement of egg production and quality

Improvement of egg production and quality

Tag Separator
Technical article
Top line
The benefits of supplying Hydroxy Methionine to aged laying hens

The benefits of supplying Hydroxy Methionine to aged laying hens

Tag Separator
Technical article

Selisseo® supports you with the following challenges in poultry

Health Management

separator
Challenge Icon

Managing the health and well-being of poultry flocks is one of the most important requirements to keep a poultry business productive and profitable.

PoultrySeparator

Heat Stress

separator
Challenge Icon

As global temperatures rise, livestock are increasingly exposed to conditions that impair their health and productivity.

PoultrySeparator
decoration

Related solutions

Product names and availability may vary by region, please contact your local Adisseo representative for more information.

Alterion
Alterion is a probiotic for poultry, promoting performance and gut balance with Bacillus subtilis.
See more
Poultry
Separator
FRA C12
FRA C12 is a practical solution to reduce the dependency on antibiotics in animal production, while maintaining animal health and performance.
See more
PoultrySwine
Separator
Adimix Precision
Adimix Precision is a coated sodium butyrate product for poultry and pig nutrition.
See more
PoultrySwine
Separator
FRA Butyrin Hybrid
FRA Butyrin Hybrid combines the benefits of glycerides of butyric acid on intestinal integrity and pathogen control in one unique concept.
See more
PoultrySwine
Separator
FRA Butyrin Ultra
The high butyric acid content of FRA Butyrin Ultra supports animal performance by improving intestinal development and integrity.
See more
PoultrySwine
Separator

I want to receive more information about Selisseo®

* required fields
Please select

The information collected from this form will be forwarded to the appropriate Adisseo department in order to manage your requests relating to our products. For more information, please refer to the information notice.

Frequently Asked Questions

What is the most effective antioxidant strategy to improve the longevity and overall performance of laying hens?

The most effective strategy combines high-quality organic selenium with antioxidant vitamins to strengthen the bird’s natural defenses and sustain performance over time.
Adisseo recommends using Selisseo® (100% hydroxy-selenomethionine, OH-SeMet) as the core selenium source, supported by Microvit® antioxidant vitamins such as Microvit® E.
This antioxidant program helps protect hens’ cells against oxidative stress, and support energy metabolism, gut integrity and egg-forming tissues. Together, Selisseo® and Microvit® contribute to prolonged laying persistency, better egg quality, and improved flock resilience, especially in aging hens.
 

How do antioxidants help reduce oxidative stress and support the health of laying hens?

Antioxidants play a central role in maintaining hen health:
•    Selisseo® (OH-SeMet) provides a highly bioavailable form of selenium that is efficiently incorporated into selenoproteins such as glutathione peroxidase: key enzymes that neutralize damaging free radicals.
•    Microvit® antioxidant vitamins (including vitamin E) protect cell membranes and help keep tissues functional under metabolic and environmental pressure.
By reducing oxidative stress, these antioxidants safeguard the liver, gut lining, reproductive system, and immune cells, helping hens maintain production, welfare, and robustness across the entire laying cycle.
 

What signs indicate that laying hens may benefit from antioxidant supplementation?

Hens may require antioxidant support when producers observe:
•    Gradual decline in laying persistency or egg output
•    Decrease in eggshell thickness or strength, or more downgraded/cracked eggs
•    Reduced egg freshness during storage (albumen quality)
•    Lower feed efficiency or poorer nutrient utilization 
•    Weaker immune responsiveness or higher susceptibility to stress
•    Declining vitality, feather quality, or resilience in aging flocks
In these situations, adding Selisseo® and complementary Microvit® antioxidants can help restore antioxidant balance and performance.
 

Which factors should poultry producers consider when choosing an antioxidant for their feeding program?

Producers should evaluate:
•    Bioavailability: Organic selenium such as OH-SeMet (Selisseo®) is more efficiently absorbed and stored than inorganic selenium or yeast-based sources.
•    Antioxidant synergy: Combining selenium with vitamin E (Microvit® E) ensures both enzymatic and membrane protection.
•    Flock age: Aging hens have higher oxidative stress and benefit the most from a strong antioxidant program.
•    Production targets: Whether the goal is egg quantity, shell quality, longer cycles, enriched eggs, or cost-optimization.
•    Regulatory and product quality: Selisseo® enhances selenium transfer to eggs, supporting “selenium-enriched egg” claims where permitted.
Selecting a high-quality, consistent and well-documented antioxidant like Selisseo®, supported by Microvit® vitamins, helps ensure reliable performance.
 

What are the economic benefits of using antioxidants to support longevity and productivity in laying hens?

A robust antioxidant strategy centered on Selisseo® and Microvit® delivers multiple economic advantages:
•    More saleable eggs thanks to improved eggshell strength and freshness
•    Better feed efficiency, lowering feed cost per egg
•    Longer productive lifespan, reducing flock replacement frequency
•    Improved selenium transfer to eggs (+50% vs sodium selenite; +20% vs seleno-yeast), enabling premium marketing when regulations allow
•    Lower losses from downgraded eggs or health-related setbacks 
•    Higher laying persistency and improved  resilience in late production
Overall, Selisseo®, supported by Microvit® antioxidant vitamins, provides a high return on investment by enhancing performance, egg quality, bird health and production longevity.

Contact us
Adisseo
© 2025 Adisseo.

You are in Europe region