Sodium butyrate is well known for having many effects in several tissues, at the cellular or microbiological level. It can be used as an energy source by epithelial cells lining the intestinal tract, reduce production of pro-inflammatory cytokines and induce the production of enteric hormones. Many of these effects increase gastro-intestinal tract (GIT) health, which is why butyrate is added to feed as performance enhancing supplement.

However, there is variability in the effect of dietary butyrate supplementation, particularly in the physiological responses that can lead to improvements in animal performance. Part of this variation can be due to differences in which regions of the GIT butyrate was delivered.

Discover why precision delivery is so important to maximise butyrate efficacy and find out more about the two main approaches which have been developed to tackle the challenge of enteric butyrate delivery.

Chapter 1. In the right place and at the right quantity – both are essential for butyrate to express its full potential

  1. Fate of unprotected sodium butyrate in GIT
  2. Delivering butyrate to the proximal part of the GIT can induce dysbiosis and/or inflammation in lower parts of the GIT

Chapter 2. Coating technology – a know-how that can’t be improvised

  1. How structural features of the coating affect butyrate release
  2. Signalling molecule

Chapter 3. Adimix Precision: unparalled precision delivery features

  1. Butyrate products have different butyrate release profiles: in vitro assessment
    1. Coated butyrate products
    2. Butyrins
  2. In vivo evaluation of butyrate products – targeted delivery throughout the GIT of broilers
  3. Delivery of butyrate in the different parts of piglet’s GIT

Chapter 4. Adimix Precision’s stability

  1. Stable butyrate content
  2. Stability of Adimix Precision’s delivery characteristics