Adisseo

Stimulating the gene expression of several selenoproteins in broilers

In animals 26 SeCys containing selenoproteins have been identified, all having essential functions, several of which directly detoxify oxidants. In chicken tissues selenium availability and stress are the main drivers for selenoprotein expression.

Selisseo, a pure form of organic selenium, provides adequate selenium levels for SeCys de novo synthesis and selenoprotein gene expression and activity.

Screening of the complete selenogenome (Cornell University, USA), in different tissues of broiler chickens, revealed that Selisseo® stimulates the expression of selenoproteins both at gene and protein levels. In particular, the expression of genes related to antioxidant function and maintenance of optimal cell selenium status was increased with Selisseo®. Further gene expression results also revealed improvements in the expression of several selenoproteins in both breast and thigh muscles. Notably several known to have antioxidant (glutathione peroxidases (GPx), methionine sulfoxide reductase B1) and anti-inflammatory functions (selenoprotein S and K). Increases were also seen in SepSecS, which is an enzyme involved in the expression of all selenoproteins. Selenoprotein P, the major selenoprotein involved in selenium homeostasis, was highly influenced by the selenium source fed.

Using Selisseo® in broilers feed helps stimulating the expression of selenoproteins gene in broilers, which guarantees a strong protection from the effects of stress.

Click on the icon below for a better understanding:

Tweets


💼 Do you want to join our team in #UnitedKingdom 🇬🇧? Become our new Technical Manager Palability! Apply: https://t.co/oJpxfe9L3N https://t.co/ZkMrNhUMLe

On #WorldHungerDay - and every day - our mission is to feed the world sustainably, safely, affordably and with high quality 🌾

More information on our commitment ➡️ https://t.co/O0PXdWk11G 🌍 https://t.co/KkJMejMY1K

🔍Christophe Paulus, Ruminant Business Director & Robert Bennett, Ruminant Category Manager, help unpack how #methionine and other products can be applied within theworld of ruminants large and small as Adisseo continues to introduce innovations ➡️ https://t.co/NaOI5YIQoDhttps://t.co/nOPr47Nzp2 Adisseo photo

#HeatStress affects #DairyCowProduction 🐮 and performance. To dial down heat stress, mechanical cooling remains a mainstay. Nutrition is of increasing importance. Research results show how methionine mitigates heat stress. To view the webinar, click here:
https://t.co/6ih6k0Jow7 https://t.co/zvGShqMqzM
Adisseo photo

⭐️ We are ranked in the top 500 Chinese brands and our chairman Hao ZHIGANG in "China Brand Day 2021 Top 10 innovative brands" ! 👏
A great recognition for all Adisseo employees for their diversity and richness 🌍

Join us ➡️ https://t.co/VKqzxy4CKl https://t.co/hFsMJRjF8u
Adisseo photo

💼 Do you want to join our team in #France 🇫🇷? Become our new Food Formulation Project Manager! Apply: https://t.co/XNOngLruru https://t.co/qEeCzXaL45